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These groups often experience more severe symptoms and longer-lasting effects [4]

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Introduction Primary Sjgren syndrome (pSS) is a systemic autoimmune disease characterised by dryness in the mouth and eyes, chronic pain and fatigue and several other extraglandular manifestations ( 2 ) indicates a positive result ( + T cells with T helper 1 (Th1) and Th2 phenotypes are present, Th17 and follicular helper T (Tfh) cells predominate and may provide a stimulus for B lymphocytes

Kainate receptors: These receptors are involved in both pre- and postsynaptic signaling and are thought to play a role in regulating synaptic transmission and plasticity

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